Cancer is most devastating when it metastasizes—when tumor cells break away, travel through the bloodstream, and then attach elsewhere, only to grow another tumor. A significant amount of scientific research has focused on finding ways to prevent metastasis. For some time, scientists have understood that a particular biochemical pathway, known as the PDK1 pathway, is active in metastasizing cancer cells. But no one knew why.
See the whole story at the link below.