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Elective list for Majors Spring 2020

UMBC Department of Chemistry and Biochemistry

CHEM 406 Bioinorganic Chemistry*, Dr. Aaron T. Smith
Areas: Inorganic Chemistry, Biochemistry. This class is designed to give the participant an overview
of how metals function in biological systems. The course comprises lectures, presentations, and
primary literature as a means to survey cutting-edge advances in the field of bioinorganic
chemistry. This class has three units: coordination chemistry of metals within biological systems;
physical and spectroscopic characterization of metal interactions within biological systems; and
mechanistic studies of metalloenzymes.

CHEM 455 Biomedicinal Chemistry*, Dr. Katherine Seley-Radtke
Areas: Organic Chemistry, Biochemistry. This survey course provides an introduction to drug design,
discovery and development processes from a biological, organic chemistry and mechanistic
standpoint. Basic principles of drug design and development, including modern rational approaches,
various drug targets, the design and mechanistic features of various classes of inhibitors and
prodrugs, DNA interactive drugs, toxicity, development of resistance, and patent issues will be
covered.

CHEM 490 Bioanalytical Lab on a Chip*, Dr. Chengpeng Chen
Area: Analytical Chemistry. This course will focus on fabrication of microfluidic devices and their
application in bioanalytical chemistry. The course material will mainly come from literature
published in high-impact journals. In this class, students will learn the general ideas of microfluidics,
as well as how to implement this technology to answer specific biological questions.

CHEM 490, Bio and Bio-Inspired Materials*, Dr. Mark Allen
Areas: Inorganic Chemistry, Biochemistry. Bio and Bio-Inspired Materials is a lecture and literature
based course designed to focus on how soft organic biomolecules interact with organic and inorganic
materials. The course has 4 units including biomolecules (proteins etc), biomineralization (how
biology makes inorganic minerals), bio-inspired synthesis (how we can mimic biology in material
preparation) and biomaterials (how materials interface with biology).

CHEM 490 Special Topics in Dynamics and Mechanism*, Dr. Bradley Arnold
Area: Physical Chemistry. Discussion of modern experimental methods and theories used to describe
chemical kinetics as applied to the elucidation of mechanisms of organic and biochemical reactions.

CHEM 490, Introduction to Fluorescence Sensing*, Dr. Marcin Ptaszek
Areas: Physical Chemistry, Biochemistry, Spectroscopy. This course introduces the principles of
fluorescence sensing as well as selected applications of fluorescence spectroscopy in analytical
chemistry, medicine and biochemistry. Topics include a survey of fluorophores, examples of
intracellular sensing of physicochemical parameters and small molecules of biological importance,
labeling of biomacro-molecules, fluorescence enzyme activity assays, and the application of
fluorescence spectroscopy in diagnosis of various diseases. The course is partly based on current
literature readings.

CHEM 490 Advanced NMR Spectroscopy*, Dr. Michael Summers
Areas: Biochemistry, Analytical Chemistry. This course focuses on theoretical aspects of solution-
state NMR spectroscopy and their applications to chemical and biological systems. NMR theory is
described using principles of classical and quantum mechanical physics. Emphasis is placed on
theories behind methods commonly used for biomolecular structure/function studies, including the
nuclear Overhauser effect, sensitivity enhancement of insensitive nuclei, and multi-dimensional NMR
methods.
*Approved as an elective for the undergraduate major in Biochemistry

Important Note

CHEM405 is only offered in spring semesters and CHEM405L is only offered in fall semesters.
B.S. CHEM majors should take CHEM 405 in the spring of their junior year.